BDBM362456 US10562916, Compound 16::US9834564, Compound 16

SMILES C(Cc1cnc2cccnc2n1)c1nc(c[nH]1)-c1ccccc1

InChI Key InChIKey=STTSEFSPVOZWTK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 362456   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sunovion Pharmaceuticals

US Patent
LigandPNGBDBM362456(US9834564, Compound 16 | US10562916, Compound 16)
Affinity DataIC50: 500nMAssay Description:The activities of the compounds were determined using the Molecular Devices IMAP PDE Fluorescence Polarization assay using recombinant human PDE-10 e...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/28/2019
Entry Details
US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Sunovion Pharmaceuticals

US Patent
LigandPNGBDBM362456(US9834564, Compound 16 | US10562916, Compound 16)
Affinity DataIC50: 500nMAssay Description:In one embodiment, the compounds provided herein were assayed for their ability to inhibit human PDE-10A. In one embodiment, the activities of the co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2020
Entry Details
US Patent