BDBM363222 (S)-1-(4-(2-chloro-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzyloxy)-2-(3-cyanobenzyloxyl)benzyl)piperidine-2-carboxylic acid::US9850225, Example 1145

SMILES OC(=O)[C@@H]1CCCCN1Cc1ccc(OCc2cccc(c2Cl)-c2ccc3OCCOc3c2)cc1OCc1cccc(c1)C#N

InChI Key InChIKey=PXUDPHSIMYUFNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363222   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM363222((S)-1-(4-(2-chloro-3-(2,3-dihydrobenzo[b][1,4]diox...)
Affinity DataIC50: 550nMAssay Description:The interaction of PD-1 and PD-L1 can be assessed using soluble, purified preparations of the extracellular domains of the two proteins. The PD-1 and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent