BDBM363709 US9850277, Compound 196

SMILES Fc1cccc(c1)N([C@H](C(=O)NC1CC(F)(F)C1)c1ccc(Cl)cc1Cl)C(=O)[C@@H]1CCC(=O)N1c1cc(ccn1)C#N

InChI Key InChIKey=YZMXTYKDFCKYEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 363709   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Agios Pharmaceuticals

US Patent
LigandPNGBDBM363709(US9850277, Compound 196)
Affinity DataIC50: 500nMAssay Description:A test compound is prepared as 10 mM stock in DMSO and diluted to 50× final concentration in DMSO, for a 50 μl reaction mixture. IDH enzyme acti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2019
Entry Details
Go to US Patent