BDBM364032 3-(4-aminopyrido[3,2-d]pyrimidin-6-yl)-N-(2-pyrrolidin-1-ylethyl)benzamide::US9855269, Compound 275

SMILES Nc1ncnc2ccc(nc12)-c1cccc(c1)C(=O)NCCN1CCCC1

InChI Key InChIKey=PXJXWOKOFSBHSY-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364032   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Genentech

US Patent

LigandBDBM364032(US9855269, Compound 275 | 3-(4-aminopyrido[3,2-d]p...)Copy SMILESCopy InChI

Affinity DataIC50: 403nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/21/2019
Entry Details
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