BDBM364041 6-(3-fluorophenyl)-N-methyl-pyrido[3,2-d]pyrimidin-4-amine::US9855269, Compound 284

SMILES CNc1ncnc2ccc(nc12)-c1cccc(F)c1

InChI Key InChIKey=MIQVXMJLPGYLPC-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 364041   

TargetMitogen-activated protein kinase kinase kinase kinase 4(Human)
Genentech

US Patent

LigandBDBM364041(US9855269, Compound 284 | 6-(3-fluorophenyl)-N-met...)Copy SMILESCopy InChI

Affinity DataIC50: 597nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
11/21/2019
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL