BDBM36498 DADMe-ImmA-p-ClPh

SMILES Nc1ncnc2c(CN3CC(O)C(CSc4ccc(Cl)cc4)C3)c[nH]c12

InChI Key InChIKey=MZZBHZOHYGEGEE-UHFFFAOYSA-N

Data  7 Kd

PDB links: 6 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 36498   

Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Neisseria meningitidis)
Albert Einstein College Of Medicine

LigandPNGBDBM36498(DADMe-ImmA-p-ClPh)
Affinity DataKd:  0.0210nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosylhomocysteine nucleosidase(Helicobacter pylori)
Albert Einstein College Of Medicine

LigandPNGBDBM36498(DADMe-ImmA-p-ClPh)
Affinity DataKd:  0.570nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Klebsiella pneumoniae)
Albert Einstein College Of Medicine

LigandPNGBDBM36498(DADMe-ImmA-p-ClPh)
Affinity DataKd:  0.5nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
TargetS-methyl-5'-thioadenosine phosphorylase(Homo sapiens (Human))
Albert Einstein College Of Medicine

LigandPNGBDBM36498(DADMe-ImmA-p-ClPh)
Affinity DataKd:  0.0100nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Escherichia coli (strain K12))
Albert Einstein College Of Medicine

LigandPNGBDBM36498(DADMe-ImmA-p-ClPh)
Affinity DataKd:  0.0000470nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
TargetAdenosylhomocysteine nucleosidase(Streptococcus pneumoniae)
Albert Einstein College Of Medicine

LigandPNGBDBM36498(DADMe-ImmA-p-ClPh)
Affinity DataKd:  0.360nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase(Staphylococcus aureus)
Albert Einstein College Of Medicine

LigandPNGBDBM36498(DADMe-ImmA-p-ClPh)
Affinity DataKd:  8nMpH: 7.5 T: 2°CAssay Description:Enzyme activity assay using various bacterial species of 5'-Methylthioadenosine nucleosidases (MTANs) excepted for MTAP, for human MTAP.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed