BDBM365272 US9868720, No. 274::[6-(1-Methyl-pyrrolidin- 3-yl)-2-(2-oxa-5-aza- bicyclo[2.2.1]hept-5-yl)- pyrimidin-4-yl]-(4- trifluoromethyl-pyridin-2- yl)-amine

SMILES CN1CCC(C1)c1cc(Nc2cc(ccn2)C(F)(F)F)nc(n1)N1CC2CC1CO2

InChI Key InChIKey=FVYMTVAOKHSVTA-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365272   

LigandPNGBDBM365272(US9868720, No. 274 | [6-(1-Methyl-pyrrolidin- 3-yl...)
Affinity DataKi:  46.3nMAssay Description:DLK kinase reactions (20 μL) containing 5 nM N-terminally GST-tagged DLK (catalytic domain amino acid 1-520) (Carna Bioscience), 40 nM N-termina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2019
Entry Details
US Patent