BDBM365841 5-{[({4-[(2-methyl-3- phenylphenyl)methoxy]phenyl} methyl)amino]methyl} pyrrolidin-2-one::US9872852, Example 93

SMILES Cc1c(COc2ccc(CNC[C@H]3CCC(=O)N3)cc2)cccc1-c1ccccc1

InChI Key InChIKey=NIVJEFTUALCIHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 365841   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM365841(5-{[({4-[(2-methyl-3- phenylphenyl)methoxy]phenyl}...)
Affinity DataIC50: 555nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
Go to US Patent