BDBM365773 (1R,2R)-2-[({2,6-dimethoxy-4-[(2- methyl-3-phenylphenyl) methoxy]phenyl}methyl)amino] cyclohexan-1-ol::US9872852, Example 25::US9872852, Example 275

SMILES COc1cc(OCc2cccc(c2C)-c2ccccc2)cc(OC)c1CN[C@@H]1CCCC[C@H]1O

InChI Key InChIKey=WRWPUUKELJIWHM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 365773   

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM365773((1R,2R)-2-[({2,6-dimethoxy-4-[(2- methyl-3-phenylp...)
Affinity DataIC50: 53nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetProgrammed cell death 1 ligand 1(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM365773((1R,2R)-2-[({2,6-dimethoxy-4-[(2- methyl-3-phenylp...)
Affinity DataIC50: 555nMAssay Description:All binding studies were performed in an HTRF assay buffer consisting of dPBS supplemented with 0.1% (withv) bovine serum albumin and 0.05% (v/v) Twe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent