BDBM366276 US9873693, Compound 199

SMILES Fc1ccc(Cn2cccc(C(=O)NC\C=C\c3ccc4\C(=C\c5ncc[nH]5)C(=O)Nc4c3)c2=O)cc1F

InChI Key InChIKey=JAFUDKKJKCLDNY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 366276   

Target3-phosphoinositide-dependent protein kinase 1 [51-360](Human)
Sunesis Pharmaceuticals

US Patent
LigandPNGBDBM366276(US9873693, Compound 199)
Affinity DataIC50: 500nMAssay Description:A PDK1 kinase assay was performed as follows. PDK1 (amino acids 51-360) and AKT2 (amino acids 140-467 fused to PIFtide, amino acids EEQEMFRDFDYIADW) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent