BDBM366973 N-[2-(3,5-dimethyl-1- piperidyl)ethyl]-4-[[8- [1-(4,4,4- trifluorobutanoyl)-3,6- dihydro-2H-pyridin-4- yl]-[1,2,4]triazolo[1,5- a]pyridin-2- yl]amino]benzamide::US9873709, Example 2-269

SMILES CC1CC(C)CN(CCNC(=O)c2ccc(Nc3nc4c(cccn4n3)C3=CCN(CC3)C(=O)CCC(F)(F)F)cc2)C1

InChI Key InChIKey=RQWBKJQXIVEUBI-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 366973   

TargetTyrosine-protein kinase JAK2(Human)
Genentech

US Patent
LigandPNGBDBM366973(N-[2-(3,5-dimethyl-1- piperidyl)ethyl]-4-[[8- [1-(...)
Affinity DataKi:  0.710nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Genentech

US Patent
LigandPNGBDBM366973(N-[2-(3,5-dimethyl-1- piperidyl)ethyl]-4-[[8- [1-(...)
Affinity DataKi:  0.880nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2019
Entry Details
US Patent