BDBM368313 US10227338, Example 100

SMILES CNCCN(C)c1cc(ccc1Nc1cc(F)c(cc1Cl)S(=O)(=O)Nc1ncc(F)cn1)C#N

InChI Key InChIKey=ZKYZLRBUFHNYEK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 368313   

TargetSodium channel protein type 9 subunit alpha(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM368313(US10227338, Example 100)
Affinity DataIC50: 1.09E+3nMAssay Description:In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

TargetSodium channel protein type 5 subunit alpha(Human)
Daewoong Pharmaceutical

US Patent
LigandPNGBDBM368313(US10227338, Example 100)
Affinity DataIC50: 1.00E+4nMAssay Description:In order to measure the sodium ion channel blocking effect, an IonFlux16 Auto patch clamp system (Fluxion, Inc.) and a plate for exclusive use were u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent