BDBM370142 US10233188, Example 31::US10800783, Example 31::US11396512, Example 31

SMILES CS(=O)(=O)N1CCC(CC1)Nc1ncc2cc(c(=O)n(C3CCCC3)c2n1)C(F)(F)C(O)=O

InChI Key InChIKey=XUPKDUPWDFWXDU-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 370142   

LigandPNGBDBM370142(US10233188, Example 31 | US10800783, Example 31 | ...)
Affinity DataKi:  0.870nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

LigandPNGBDBM370142(US10233188, Example 31 | US10800783, Example 31 | ...)
Affinity DataKi:  0.870nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370142(US10233188, Example 31 | US10800783, Example 31 | ...)
Affinity DataKi:  0.870nMAssay Description:The purpose of the CDK6/Cyclin D1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) in the presence of small molecule inhibitor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent

LigandPNGBDBM370142(US10233188, Example 31 | US10800783, Example 31 | ...)
Affinity DataKi:  2.43nMAssay Description:The purpose of the CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

LigandPNGBDBM370142(US10233188, Example 31 | US10800783, Example 31 | ...)
Affinity DataKi:  2.43nMAssay Description:The mobility shift assay electrophoretically separates the fluorescently labeled peptides (substrate and phosphorylated product) following the kinase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2022
Entry Details
US Patent

LigandPNGBDBM370142(US10233188, Example 31 | US10800783, Example 31 | ...)
Affinity DataKi:  2.43nMAssay Description:The purpose of the CDK2/Cyclin E1 assay is to evaluate the inhibition (% inhibition, Kiapp and Ki values) of small molecule inhibitors by using a flu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent