BDBM370491 1-(4-(cyclopropylmethylene)cyclohexyl)-2-(6- fluoro-5H-imidazo[5,1-a]isoindol-5-yl)ethanol;::US10233190, Example 1410

SMILES OC(CC1c2c(cccc2F)-c2cncn12)C1CCC(CC1)=CC1CC1

InChI Key InChIKey=PRUMALLZQVUWMP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370491   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandPNGBDBM370491(1-(4-(cyclopropylmethylene)cyclohexyl)-2-(6- fluor...)
Affinity DataIC50: 1.00E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent