BDBM370518 2-(5H-imidazo[5,1-a]isoindol-5-yl)-1- (spiro[2.5]octan-6-yl)ethanol::US10233190, Example 1438

SMILES OC(CC1c2ccccc2-c2cncn12)C1CCC2(CC2)CC1

InChI Key InChIKey=SMPOUDVZNQHGAJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 370518   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Newlink Genetics

US Patent
LigandPNGBDBM370518(2-(5H-imidazo[5,1-a]isoindol-5-yl)-1- (spiro[2.5]o...)
Affinity DataIC50: 5.50E+3nMAssay Description:The IC50 values for each compound were determined by testing the activity of IDO in a mixture containing 50 mM potassium phosphate buffer at pH 6.5; ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2019
Entry Details
US Patent