BDBM371531 (racemic)-4-chloro-2-methyl-5-((tetrahydro-2H-pyran-3-yl)amino)pyridazin-::US10239861, Example 11

SMILES CN1C=C(Cl)C(NC2CCCOC2)=CN1

InChI Key InChIKey=QSVIXXIANJJWBT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 371531   

TargetHistone acetyltransferase KAT2B(Human)
Genetech

US Patent
LigandChemical structure of BindingDB Monomer ID 371531BDBM371531((racemic)-4-chloro-2-methyl-5-((tetrahydro-2H-pyra...)
Affinity DataIC50: 1.02E+3nMAssay Description:His/Flag epitope tagged PCAF719-832 bromodomain was cloned, expressed and purified to homogeneity in-house. PCAF bromodomain binding and inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/30/2019
Entry Details
US Patent