BDBM373113 1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-(2- phenylimidazo[1,2- a]pyrimidin-3- yl)urea::US9896447, Compound 30

SMILES O=C(Nc1c(nc2ccccn12)-c1ccccc1)Nc1c(nc2ncccn12)-c1ccccc1

InChI Key InChIKey=SHDBJUBNOSEBEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 373113   

TargetHigh affinity nerve growth factor receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM373113(1-(2- phenylimidazo[1,2- a]pyridin-3-yl)-3-(2- phe...)
Affinity DataIC50: 1.50E+3nMAssay Description:TrkA functional activity was measured using a DiscoverX PathHunter assay. In this assay, U2OS cells are express TrkA receptor as a fusion with the we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent