BDBM374330 (S)-(6-(6-(6-(1-aminopropyl)pyridin-2-yl)-4-(2-methoxyethoxy)-1H-indazol-1-yl)pyrazin-2-yl)methanol::US10246456, Example 482::US10577367, Example 482

SMILES CC[C@H](N)c1cccc(n1)-c1cc(OCCOC)c2cnn(-c3cncc(CO)n3)c2c1

InChI Key InChIKey=HFHOIHABNJPOMK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 374330   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM374330(US10246456, Example 482 | (S)-(6-(6-(6-(1-aminopro...)
Affinity DataIC50: 100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/21/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Biogen Ma

US Patent
LigandPNGBDBM374330(US10246456, Example 482 | (S)-(6-(6-(6-(1-aminopro...)
Affinity DataIC50: 100nMAssay Description:The biochemical assay is in a AlphaScreen format. The kinase reaction is based on the IRAK-4 phosphorylation of a biotin labeled peptide. The phospho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2020
Entry Details
US Patent