BDBM37478 1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-(2-thienyl)urea::1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl-urea::1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-ylurea::MLS000119982::SMR000096899::cid_4101591

SMILES CCOc1ccc2nc(NC(=O)Nc3cccs3)sc2c1

InChI Key InChIKey=JBLGCZDPPLPWSW-UHFFFAOYSA-N

Data  9 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 37478   

TargetSphingosine 1-phosphate receptor 3(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataIC50: 1.66E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay
TargetTranscription factor p65(Human)
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataEC50:  1.68E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2011
Entry Details
PCBioAssay
TargetCaspase-3(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataIC50: 2.99E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetSentrin-specific protease 8(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataIC50: 2.41E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetSentrin-specific protease 6(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataIC50: 1.92E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetOxysterols receptor LXR-beta(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataEC50:  6.75E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Photinus pyralis luciferase by Steady-Glo reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of Photinus pyralis luciferase by BrightGlo reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of Photinus pyralis luciferase by PK-Light assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataIC50: 600nMAssay Description:Inhibition of Photinus pyralis luciferaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetLuciferin 4-monooxygenase(Common eastern firefly)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM37478(1-(6-ethoxy-1,3-benzothiazol-2-yl)-3-thiophen-2-yl...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Photinus pyralis luciferase by Easy lite assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed