BDBM37542 1-(4-cyclopentyl-1-piperazinyl)-3-methyl-4-pyrido[1,2-a]benzimidazolecarbonitrile::1-(4-cyclopentylpiperazin-1-yl)-3-methyl-pyrido[1,2-a]benzimidazole-4-carbonitrile::1-(4-cyclopentylpiperazin-1-yl)-3-methylpyrido[1,2-a]benzimidazole-4-carbonitrile::1-(4-cyclopentylpiperazino)-3-methyl-pyrido[1,2-a]benzimidazole-4-carbonitrile::MLS000039270::SMR000035372::cid_660337

SMILES Cc1cc(N2CCN(CC2)C2CCCC2)n2c(nc3ccccc23)c1C#N

InChI Key InChIKey=GSOYKOOBWAVEGP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37542   

TargetHuntingtin(Human)
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM37542(1-(4-cyclopentylpiperazin-1-yl)-3-methyl-pyrido[1,...)
Affinity DataIC50: 8.00E+3nMAssay Description:The mutation underlying Huntington's disease is an expansion of a polyglutamine tract in the N-terminus of the protein huntingtin (htt). Under no...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay