BDBM376287 US9914740, II-3

SMILES CNC(=O)[C@@H](NC(=O)c1ccc-2c(OCc3cnccc-23)c1)c1ccccc1Cl

InChI Key InChIKey=MZVSDJGCELEHMH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376287   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376287(US9914740, II-3)
Affinity DataIC50: 25.4nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent