BDBM376299 (R)-methyl 2- (2-chlorophenyl)-2- (5H-chromeno [3,4-c]pyridine-8- carboxamido)acetate::US9914740, II-15

SMILES COC(=O)[C@H](NC(=O)c1ccc-2c(OCc3cnccc-23)c1)c1ccccc1Cl

InChI Key InChIKey=IXBLUTWFVTVZOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376299   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376299(US9914740, II-15 | (R)-methyl 2- (2-chlorophenyl)-...)
Affinity DataIC50: 756nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
US Patent