BDBM376339 Methyl 3-((5-methyl-5H-chromeno[3,4-c]pyridine-8-carboxamido)methyl)benzoate::US9914740, V-1

SMILES COC(=O)c1cccc(CNC(=O)c2ccc-3c(OC(C)c4cnccc-34)c2)c1

InChI Key InChIKey=SQYQKJZDVFVROX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376339   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376339(US9914740, V-1 | Methyl 3-((5-methyl-5H-chromeno[3...)
Affinity DataIC50: 30.2nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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