BDBM376346 N-(3-carbamoyl- benzyl)-5- methyl-5H- chromeno[3,4-c] pyridine-8- carboxamide::US9914740, V-8

SMILES CC1Oc2cc(ccc2-c2ccncc12)C(=O)NCc1cccc(c1)C(N)=O

InChI Key InChIKey=VJTZAQPYHJFUCL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 376346   

TargetRho-associated protein kinase 2(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM376346(US9914740, V-8 | N-(3-carbamoyl- benzyl)-5- methyl...)
Affinity DataIC50: 42.4nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2020
Entry Details
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