BDBM377934 4-acetyl-N-((1r,4r)-4-aminocyclohexyl)-1H-pyrrole-2-carboxamide::US10266526, Compound 64

SMILES CC(=O)c1c[nH]c(c1)C(=O)N[C@H]1CC[C@H](N)CC1

InChI Key InChIKey=JXYCFANEPYQFCE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377934   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM377934(4-acetyl-N-((1r,4r)-4-aminocyclohexyl)-1H-pyrrole-...)
Affinity DataIC50: 1.34E+5nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
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