BDBM377975 US10266526, Compound 104::ethyl 2-(1-(L-alanyl)piperidin-4-yl)-2-(2-oxoindoline-5-carboxamido)acetate

SMILES CCOC(=O)C(NC(=O)c1ccc2NC(=O)Cc2c1)C1CCN(CC1)C(=O)[C@H](C)N

InChI Key InChIKey=GEDNLZVZYMUPDK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377975   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM377975(ethyl 2-(1-(L-alanyl)piperidin-4-yl)-2-(2-oxoindol...)
Affinity DataIC50: 1.51E+3nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent