BDBM377994 US10266526, Compound 122::ethyl 2-(2-oxoindoline-5-carboxamido)-2-(piperidin-4-yl)acetate

SMILES CCOC(=O)C(NC(=O)c1ccc2NC(=O)Cc2c1)C1CCNCC1

InChI Key InChIKey=FWWPTKHIBNSGKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 377994   

TargetHistone-lysine N-methyltransferase SMYD3(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM377994(US10266526, Compound 122 | ethyl 2-(2-oxoindoline-...)
Affinity DataIC50:  4.23E+4nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent