BDBM378386 N-(4-aminocyclohexyl)-1H-imidazole-4-carboxamide::US10266526, Compound 517

SMILES NC1CCC(CC1)NC(=O)c1c[nH]cn1

InChI Key InChIKey=NJXKOIRMNPBREV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378386   

TargetHistone-lysine N-methyltransferase SMYD3(Human)
Epizyme

US Patent
LigandPNGBDBM378386(N-(4-aminocyclohexyl)-1H-imidazole-4-carboxamide |...)
Affinity DataIC50: 5.00E+4nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2020
Entry Details
US Patent