BDBM37862 1-[2-(4-methoxyphenyl)sulfonyl-5-oxidanylidene-1H-pyrazol-3-yl]-3-thiophen-2-yl-urea::1-[2-(4-methoxyphenyl)sulfonyl-5-oxo-1H-pyrazol-3-yl]-3-thiophen-2-ylurea::1-[5-keto-2-(4-methoxyphenyl)sulfonyl-3-pyrazolin-3-yl]-3-(2-thienyl)urea::PC-0094945::PCMD-CC-MCM-25::cid_11834390

SMILES COc1ccc(cc1)S(=O)(=O)n1[nH]c(=O)cc1NC(=O)Nc1cccs1

InChI Key InChIKey=KUCBAVIFGIBJLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 37862   

TargetCathepsin B(Human)
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM37862(PCMD-CC-MCM-25 | 1-[2-(4-methoxyphenyl)sulfonyl-5-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Human liver cathepsin B (EC 3.4.22.1) is a lysosomal cysteine protease. There has been a recent resurgence of interest in cathepsin B due to research...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2011
Entry Details
PCBioAssay