BDBM378953 2-{1-(2,6- dichloro-3- (trifluoromethyl) benzyl]-1H- indazol-3-yl}-5- methoxy-N- (pyridin-4- yl)pyrimidin-4- amine::US10266548, Example 2-34-1

SMILES COc1cnc(nc1NC1=CCNC=C1)-c1nn(Cc2c(Cl)ccc(c2Cl)C(F)(F)F)c2ccccc12

InChI Key InChIKey=MLSQBNAEAJLLEA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 378953   

TargetMitotic checkpoint serine/threonine-protein kinase BUB1(Human)
Bayer Intellectual Property

US Patent
LigandChemical structure of BindingDB Monomer ID 378953BDBM378953(US10266548, Example 2-34-1 | 2-{1-(2,6- dichloro-3...)
Affinity DataIC50: 38nMAssay Description:Bub1-inhibitory activities of compounds described in the present invention were quantified using a time-resolved fluorescence energy transfer (TR-FRE...More data for this Ligand-Target Pair
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Date in BDB:
2/7/2020
Entry Details
US Patent