BDBM380581 US9926330, 3-3::trans-N'-{6-[(1E)-3-methoxyprop- 1-en-1-yl]quinazolin-4-yl}-N,N- dimethylcyclohexane-1,4-diamine

SMILES COC\C=C\c1ccc2ncnc(N[C@H]3CC[C@@H](CC3)N(C)C)c2c1

InChI Key InChIKey=SZLPCEFKYABVOG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 380581   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM380581(US9926330, 3-3 | trans-N'-{6-[(1E)-3-methoxyprop- ...)
Affinity DataIC50: 54nMAssay Description:The kinase activity of IRAK4 is determined by its ability to catalyze the phosphorylation of a fluorescent polypeptide substrate. The extent of phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2020
Entry Details
US Patent