BDBM382072 2-[5-(4-fluorophenyl)-1-(2,2,2- trifluoroethyl)imidazol-4-yl]-4- (2H-tetrazol-5-yl)pyridine::US10273222, Example 134

SMILES Fc1ccc(-c2c(-c3cc(-c4nn[nH]n4)ccn3)ncn2CC(F)(F)F)cc1

InChI Key InChIKey=YPXMBUYRTBIECY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 382072   

TargetLysine-specific demethylase 2B(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382072BDBM382072(2-[5-(4-fluorophenyl)-1-(2,2,2- trifluoroethyl)imi...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382072BDBM382072(2-[5-(4-fluorophenyl)-1-(2,2,2- trifluoroethyl)imi...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent