BDBM382084 2-[1-(1,2,3,4- tetrahydronaphthalen-2- ylmethyl)imidazol-4-yl]-4-(2H- tetrazol-5-yl)pyridine::US10273222, Example 146

SMILES c1ccc2c(c1)CCC(Cn1cnc(-c3cc(-c4nn[nH]n4)ccn3)c1)C2

InChI Key InChIKey=BPQJRTYHBQULJV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 382084   

TargetLysine-specific demethylase 2B(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382084BDBM382084(2-[1-(1,2,3,4- tetrahydronaphthalen-2- ylmethyl)im...)
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent

TargetLysine-specific demethylase 4C(Human)
Celgene Quantscel Research

US Patent
LigandChemical structure of BindingDB Monomer ID 382084BDBM382084(2-[1-(1,2,3,4- tetrahydronaphthalen-2- ylmethyl)im...)
Affinity DataIC50: 5.50E+3nMAssay Description:The ability of test compounds to inhibit the activity of JMJD2C was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details
US Patent