BDBM383527 US10280149, Example 36::[1-(cyclopropylmethyl)-3-piperidyl]-(6-phenyl-3-pyridyl)methanone

SMILES O=C(C1CCCN(CC2CC2)C1)c1ccc(nc1)-c1ccccc1

InChI Key InChIKey=ZPXBVOHQRVDIFP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383527   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383527BDBM383527([1-(cyclopropylmethyl)-3-piperidyl]-(6-phenyl-3-py...)
Affinity DataIC50: 533nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent