BDBM383536 3-(1-cyclopentylpiperidine-3-carbonyl)naphthalene-1-carbonitrile::US10280149, Example 45

SMILES O=C(C1CCCN(C1)C1CCCC1)c1cc(C#N)c2ccccc2c1

InChI Key InChIKey=WEDXWDRDYGPCBI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383536   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383536BDBM383536(3-(1-cyclopentylpiperidine-3-carbonyl)naphthalene-...)
Affinity DataIC50: 267nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent