BDBM383556 3-[3-(6-methoxynaphthalene-2-carbonyl)-1-piperidyl]cyclobutanecarbonitrite::US10280149, Example 65

SMILES COc1ccc2cc(C(=O)C3CCCN(C4CC(C#N)C4)C3)ccc2c1

InChI Key InChIKey=ULAGITALVLRTEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383556   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383556BDBM383556(3-[3-(6-methoxynaphthalene-2-carbonyl)-1-piperidyl...)
Affinity DataIC50: 309nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent