BDBM383589 2,3-dihydro-1,4-benzodioxin-6-yl-(1-propyl-3-piperidyl)methanone::US10280149, Example 108

SMILES CCCN1CCCC(C1)C(=O)c1ccc2OCCOc2c1

InChI Key InChIKey=FDGCVYBHNZIQQX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 383589   

TargetLysine-specific demethylase 2B(Human)
Genentech

US Patent
LigandChemical structure of BindingDB Monomer ID 383589BDBM383589(2,3-dihydro-1,4-benzodioxin-6-yl-(1-propyl-3-piper...)
Affinity DataIC50: 297nMAssay Description:Full length KDM2B was cloned, expressed, and purified to homogeneity. Compound inhibition of KDM2B demethylase activity was assessed by monitoring th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2020
Entry Details
US Patent