BDBM384976 2-(dimethylamino)-6-oxo-N- {pyridin-4-yl[4- (trifluoromethyl)phenyl]methyl}- 1,6-dihydropyrimidine-4- carboxamide::US10285989, Example 196

SMILES CN(C)c1nc(cc(=O)[nH]1)C(=O)NC(c1ccncc1)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ATFBQZKIYNYWHI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384976   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384976(2-(dimethylamino)-6-oxo-N- {pyridin-4-yl[4- (trifl...)
Affinity DataKi:  91nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
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