BDBM384985 US10285989, Example 205::methyl ({[2-(dimethylamino)-6- oxo-1,6-dihydropyrimidin-4- yl]carbonyl}amino)[4- (trifluoromethyl)phenyl]acetate

SMILES COC(=O)C(NC(=O)c1cc(=O)[nH]c(n1)N(C)C)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=KUWQWDLUIAZOIY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 384985   

TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM384985(methyl ({[2-(dimethylamino)-6- oxo-1,6-dihydropyri...)
Affinity DataKi:  49nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
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Date in BDB:
2/27/2020
Entry Details
US Patent