BDBM385796 2-(dimethylamino)ethyl N-[5- (4-cyano-3-fluorophenyl)- [1,2,4]triazolo[1,5-a]pyridin- 7-yl]carbamate::US10287286, Example 199

SMILES CN(C)CCOC(=O)Nc1cc(-c2ccc(C#N)c(F)c2)n2ncnc2c1

InChI Key InChIKey=VYXDUACUDNVIPB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 385796   

TargetProlyl hydroxylase EGLN2(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM385796(2-(dimethylamino)ethyl N-[5- (4-cyano-3-fluorophen...)
Affinity DataIC50: 111nMAssay Description:The IC50 values for the PHD1 enzyme (residues 1-407) were determined by mixing increasing amounts of a compound of the invention with a fixed amount ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/29/2020
Entry Details
US Patent