BDBM386410 (2S,4R)-1-(2-(3- acetyl-5-(2- methylpyrimidin- 5-yl)-1H-indazol- 1-yl)acetyl)-N- (2'-chloro-5'- (N,N- dimethylsulfamoyl)- 2-fluoro-[1,1'- biphenyl]-3-yl)-4- fluoropyrrolidine- 2-carboxamide::US10287301, Compound 343::US10822352, Comp No. 343

SMILES CN(C)S(=O)(=O)c1ccc(Cl)c(c1)-c1cccc(NC(=O)[C@@H]2C[C@@H](F)CN2C(=O)Cn2nc(C(C)=O)c3cc(ccc23)-c2cnc(C)nc2)c1F

InChI Key InChIKey=ZEJAWACPRFOOES-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 386410   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM386410(US10287301, Compound 343 | (2S,4R)-1-(2-(3- acetyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2021
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM386410(US10287301, Compound 343 | (2S,4R)-1-(2-(3- acetyl...)
Affinity DataIC50: 1.00E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration was incubated with test compound at various conc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2020
Entry Details
US Patent