BDBM388050 US10294229, Example 199::US10294229, Example 204

SMILES CC(C)Nc1cc(ncc1-c1cn(nn1)[C@@H]1CCN(C[C@H]1O)S(C)(=O)=O)-n1ncc2cc(cnc12)C#N

InChI Key InChIKey=GBYXJRJXGWQDCI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 388050   

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM388050(US10294229, Example 199 | US10294229, Example 204)
Affinity DataIC50: 4nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent

TargetInterleukin-1 receptor-associated kinase 4(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM388050(US10294229, Example 199 | US10294229, Example 204)
Affinity DataIC50: 6nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μL prepared from 15 μL additions of enzyme and substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details
US Patent