BDBM389200 US9951027, 2-27-2

SMILES CC1C[C@@H](CC(C)(C)C1)n1c(Nc2ccc(cc2)S(C)(=O)=O)nc2cc(ccc12)C(O)=O

InChI Key InChIKey=JUIHDONOSWCBIL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 389200   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic [R132H](Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM389200(US9951027, 2-27-2)
Affinity DataIC50: 3.30E+3nMAssay Description:mIDH1 catalyzes the NADPH-dependent reduction of alpha-ketoglutarate (α-KG) to (2R)-2-hydroxyglutarate (2-HG). NADPH consumption was measured by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent