BDBM389990 4-amino-3-(4-phenoxyphenyl)-1- [[(2R)-1-prop-2-enoylpyrrolidin-2- yl]methyl]-6H-pyrrolo[2,3- d]pyridazin-7-one::US10323037, Example 7::US9951077, 7

SMILES Nc1n[nH]c(=O)c2n(C[C@H]3CCCN3C(=O)C=C)cc(-c3ccc(Oc4ccccc4)cc3)c12

InChI Key InChIKey=DGTWDYANCVYFCB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 389990   

TargetTyrosine-protein kinase BTK(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM389990(4-amino-3-(4-phenoxyphenyl)-1- [[(2R)-1-prop-2-eno...)
Affinity DataIC50: 5.05E+4nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Jiangsu Hengrui Medicine

US Patent
LigandPNGBDBM389990(4-amino-3-(4-phenoxyphenyl)-1- [[(2R)-1-prop-2-eno...)
Affinity DataIC50: 5.01E+4nMAssay Description:The Btk kinase assay was performed using a ADP-Glo Btk kinase assay kit purchased from Promega (Madison, Wis.). The assay was conducted according to ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
US Patent