BDBM39176 3-chloranyl-4-(4-methylpiperazin-1-yl)-1-(3-nitrophenyl)pyrrole-2,5-dione::3-chloro-1-(3-nitrophenyl)-4-(4-Methylpiperazin-1-yl)-1H-pyrrole-2,5-dione::3-chloro-4-(4-methyl-1-piperazinyl)-1-(3-nitrophenyl)pyrrole-2,5-dione::3-chloro-4-(4-methylpiperazin-1-yl)-1-(3-nitrophenyl)pyrrole-2,5-dione::3-chloro-4-(4-methylpiperazino)-1-(3-nitrophenyl)-3-pyrroline-2,5-quinone::CHEMBL1271883::MLS-0111745.0001::cid_16654772

SMILES CN1CCN(CC1)C1=C(Cl)C(=O)N(C1=O)c1cccc(c1)[N+]([O-])=O

InChI Key InChIKey=JMAKPLURQLXSHD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 39176   

TargetBcl-2-related protein A1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM39176(3-chloranyl-4-(4-methylpiperazin-1-yl)-1-(3-nitrop...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by time resolved-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed
TargetBcl-2-related protein A1(Mouse)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39176(3-chloranyl-4-(4-methylpiperazin-1-yl)-1-(3-nitrop...)
Affinity DataIC50: 3.94E+3nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (San Diego, CA) NIH Molecular Libraries Screening Cen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/30/2011
Entry Details
PCBioAssay
TargetBcl-2-related protein A1(Mouse)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM39176(3-chloranyl-4-(4-methylpiperazin-1-yl)-1-(3-nitrop...)
Affinity DataIC50: 6.79E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2011
Entry Details
PCBioAssay
TargetBcl-2-related protein A1(Human)
Human Biomolecular Research Institute

Curated by ChEMBL
LigandPNGBDBM39176(3-chloranyl-4-(4-methylpiperazin-1-yl)-1-(3-nitrop...)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of N-terminal FITC BH3 peptide binding to GST-tagged Bfl1 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2011
Entry Details Article
PubMed