BDBM395051 3-[({5-[3- (trifluoromethyl) benzoyl]pyrimidin- 2- yl}amino)methyl] benzonitrile::US10308615, Example 62

SMILES FC(F)(F)c1cccc(c1)C(=O)c1cnc(NCc2cccc(c2)C#N)nc1

InChI Key InChIKey=SXZCWPNJVJNMGU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 395051   

TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395051(3-[({5-[3- (trifluoromethyl) benzoyl]pyrimidin- 2...)
Affinity DataIC50: >123nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395051(3-[({5-[3- (trifluoromethyl) benzoyl]pyrimidin- 2...)
Affinity DataIC50:  150nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent