BDBM395115 4-[({5-[3- (methylsulfonyl) benzoyl]pyrimidin- 2- yl}amino)methyl] benzonitrile::US10308615, Example 126

SMILES CS(=O)(=O)c1cccc(c1)C(=O)c1cnc(NCc2ccc(cc2)C#N)nc1

InChI Key InChIKey=MDVMDFSDEZBTKJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395115   

TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395115(4-[({5-[3- (methylsulfonyl) benzoyl]pyrimidin- 2-...)
Affinity DataIC50:  28.2nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395115(4-[({5-[3- (methylsulfonyl) benzoyl]pyrimidin- 2-...)
Affinity DataIC50:  40.6nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPantetheinase(Homo sapiens (Human))
Pfizer

US Patent
LigandPNGBDBM395115(4-[({5-[3- (methylsulfonyl) benzoyl]pyrimidin- 2-...)
Affinity DataIC50:  44nMAssay Description:The vanin-1 protein was prepared in-house from a construct expressing the extracellular domain of human vanin-1 (GenBank ID NM_004666) preceded N-ter...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent