BDBM395587 (R)-1-((7-cyano-2- (3'-(3-(((1-hydroxy- cyclopropyl)methyl- amino)methyl)-1,7- naphthyridin-8- ylamino)-2,2'- dimethylbiphenyl- 3-yl)benzo[d]oxazol-::US10308644, Example 199::US10800768, Example 199::US11339149, Example 199

SMILES Cc1c(Nc2nccc3cc(CNCC4(O)CC4)cnc23)cccc1-c1cccc(-c2nc3cc(CN4CC[C@](C)(C4)C(O)=O)cc(C#N)c3o2)c1C

InChI Key InChIKey=SQWBBMMBPIUVOQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 395587   

LigandPNGBDBM395587(US10308644, Example 199 | (R)-1-((7-cyano-2- (3'-(...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent

LigandPNGBDBM395587(US10308644, Example 199 | (R)-1-((7-cyano-2- (3'-(...)
Affinity DataIC50: 3.00E+3nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2021
Entry Details
US Patent

LigandPNGBDBM395587(US10308644, Example 199 | (R)-1-((7-cyano-2- (3'-(...)
Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2022
Entry Details
US Patent