BDBM395659 (R)-4-((2-(2-chloro-3′-(7-cyano-5-((3-hydroxypyrrolidin-1-yl)methyl)benzo[d]oxazol-2-yl)-2′-methylbiphenyl-3-ylcarbamoyl)-1-methyl-6,7-dihydro-1H-imidazo[4,5-c]pyridin-5(4H)-yl)methyl)-1-methylcyclohexanecarboxylic acid (Peak 2)::US10308644, Example 269

SMILES Cc1c(cccc1-c1cccc(NC(=O)c2nc3CN(CC4CCC(C)(CC4)C(O)=O)CCc3n2C)c1Cl)-c1nc2cc(CN3CC[C@@H](O)C3)cc(C#N)c2o1

InChI Key InChIKey=DFNCTCNXTIXNNA-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395659   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Human)
Incyte

US Patent

LigandBDBM395659(US10308644, Example 269 | (R)-4-((2-(2-chloro-3...)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 uL. Inhibitors were first serially diluted in DMSO...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/15/2020
Entry Details
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