BDBM395992 US10308660, Example 93

SMILES CC1(CN)CCN(CC1)c1ncc(Sc2cccc(Cl)c2Cl)c(=O)[nH]1

InChI Key InChIKey=GRRBHLXZWPXFAX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 395992   

LigandPNGBDBM395992(US10308660, Example 93)
Affinity DataIC50: 65nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2020
Entry Details
US Patent